Decorticate Female Rats and Reproductive Functions
نویسنده
چکیده
Hooded rats were operated to achieve maximum removal of cortical tissue (decorticationDC). DC was achieved which was later confirmed by serial histology. The rats and well matched controls were studied as to their reproductive cyclicity using vaginal smear technique, and their ability to achieve functional oestrus and mating – including pregnancy. From histological demonstrations, two groups of animals emerged – DC with intact olfactory cortex and DC without olfactory cortex. Generally all DC rats did not cycle normally unless kept in a male cage. Olfactory DC rats did not cycle at all and did not become pregnant. Non-olfactory DC rats became pregnant when exposed to male and were able to carry pregnancy to term in varying degrees of success. It was concluded that decortication impairs reproductive function in the female rat and that this may be due to impairment of hypothalamic function. The possible role of local control of reproduction in DC rats is mentioned.
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